Amino-functionalized coatings are a key component in many established applications in the life sciences. Amine groups can for example be used for coupling RNA, DNA, proteins and other functional biomolecules to a substrate. Our AziGrip4™ Amine coating provide an increased amine surface density, improved accessibility of the amino-groups due to a spontaneously formed nano-roughness, and a dramatically higher stability compared to the currently used aminosilane coatings.
Coating description: AziGrip4™ Amine nanostructured surface
Substrate examples: glass, quartz, silicon wafers, polyolefins (COC and COP), (plasma-activated) polymers, metal oxides (Al2O3, Ta2O5, ITO, TiO2, ZrO2, Fe2O3)
Immobilization mechanism: Electrostatic adsorption followed by a UVC or temperature-induced cross-linking reaction
- Coated standard microscope slides – Please ask for a quote here!
- Specific customer-specific substrates – Contact our sales team for more information!
Key Product Features:
- Increased amine surface density and amine availability due to nano-roughness
- 1-year shelf life
- Stable against various chemicals and solvents (boiling alcohols such as ethanol or 2-propanol, water, elevated pH and temperature)
- Tunable amine surface density
- Tunable hydrophilicity for controlling drop spreading during printing, or for optimizing microchannel wettability
- Suitable for inorganic (e.g. glass) and organic (e.g. polystyrene) applications
- Printable down to 40 µm resolution
- Suitable for patterning (in combination with non-fouling coatings) on chips and inside microfluidic channels
- Protein binding inside microfluidic patterns
- Support for particle binding
- Array CGH
- Transcriptional profiling
- SNP genotyping
- Splice variant detection
- DNA methylation profiling